Will Bolton
Will Bolton
Home
Experience
Projects
Publications
Talks & Conferences
Contact
Light
Dark
Automatic
Paper-Conference
Adversarial Fast-Moving Real-World Domains as Test Beds for Benchmarking AI Scientist Capabilities
A framework for benchmarking AI scientist capabilities using adversarial, fast-moving real-world domains, where expert practitioners independently produce observable ground truth after an information cutoff. Instantiated in Formula 1 car design for the 2026 regulations and Magic: The Gathering deck building, with frontier models ideating from pre-cutoff information only and their outputs scored against real innovations and Pro Tour decklists.
William Bolton
,
Philip Torr
PDF
Source
Cite
Code (F1)
Code (MTG)
Poster
Learning Clinical-Trial Strategy: Offline Policy Training for Decision Agents
Framing oncology clinical development as an offline decision-making problem, where an agent predicts the next six-month trial portfolio of a drug programme from information available at the decision date. Built on a temporal dataset of 31.7k public records turned into 881 decision episodes across 45 historical programmes, used to train offline policies and compare them against frontier LLM agents on held-out drug, sponsor, drug-class and temporal splits.
William Bolton
,
Philip Torr
PDF
Source
Cite
Code
Dataset
Poster
RAmBLA: Reliability AssesMent for Biomedical LLM Assistants
A framework for evaluating the reliability of LLMs as assistants in the biomedical domain
William Bolton
,
Rafael Poyiadzi
,
Edward Morrell
,
Gabriela Van Bergen Gonzalez Bueno
,
Lea Goetz
PDF
Source
Cite
Code
GSK.ai write-up
Poster
Co-morbidity Representation in Artificial Intelligence: Tapping into Unused Clinical Knowledge
A innovative pipeline that uses clinical ontologies to generate comorbidity and patient representations for downstream AI tasks.
William Bolton
,
Pantelis Georgiou
,
Alison Holmes
,
Timothy Rawson
PDF
Source
Cite
Code
Poster
Slides
Cite
×